Localized spectroscopy from anatomically matched compartments: improved sensitivity and localization for Cardiac31P MRS in humans
R Löffler, R Sauter, H Kolem, A Haase… - Journal of Magnetic …, 1998 - Elsevier
Several pioneering studies have demonstrated that localized31P NMR spectroscopy of the
human heart might become an important diagnostic tool in cardiology. The main limitation is
due to the low sensitivity of these experiments, allowing only crude spatial resolution. We
have implemented a three-dimensional version of SLOOP (“spectral localization with optimal
pointspread function”) on a clinical instrument. SLOOP takes advantage of all availablea
prioriinformation to match the size and the shape of the sensitive volumes to the anatomical …
human heart might become an important diagnostic tool in cardiology. The main limitation is
due to the low sensitivity of these experiments, allowing only crude spatial resolution. We
have implemented a three-dimensional version of SLOOP (“spectral localization with optimal
pointspread function”) on a clinical instrument. SLOOP takes advantage of all availablea
prioriinformation to match the size and the shape of the sensitive volumes to the anatomical …