[HTML][HTML] Pulmonary surfactant: functions and molecular composition
J Goerke - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 1998 - Elsevier
J Goerke
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1998•ElsevierThis review briefly notes recent findings important for understanding the surface mechanical
functions of pulmonary surfactant. Currently known surfactant-specific proteins and lipids are
discussed, with an eye to their possible functions. Competing models of the alveolar
subphase life cycle of surfactant are also presented. It is concluded that, in spite of much
effort, we still do not understand the basic molecular mechanisms underlying surfactant's
rapid adsorption to the air-water interface.
functions of pulmonary surfactant. Currently known surfactant-specific proteins and lipids are
discussed, with an eye to their possible functions. Competing models of the alveolar
subphase life cycle of surfactant are also presented. It is concluded that, in spite of much
effort, we still do not understand the basic molecular mechanisms underlying surfactant's
rapid adsorption to the air-water interface.
This review briefly notes recent findings important for understanding the surface mechanical functions of pulmonary surfactant. Currently known surfactant-specific proteins and lipids are discussed, with an eye to their possible functions. Competing models of the alveolar subphase life cycle of surfactant are also presented. It is concluded that, in spite of much effort, we still do not understand the basic molecular mechanisms underlying surfactant’s rapid adsorption to the air-water interface.
Elsevier