Immunohistochemical localization and distribution of VIP/PACAP receptors in human lung☆
R Busto, JC Prieto, G Bodega, J Zapatero, I Carrero - Peptides, 2000 - Elsevier
VIP and PACAP are distributed in nerve fibers throughout the respiratory tract acting as
potent bronchodilators and secretory agents. By using RT-PCR and immunoblotting
techniques, we have previously shown the expression of common VIP/PACAP (VPAC1 and
VPAC2) and specific PACAP (PAC1) receptors in human lung. Here we extend our aims to
investigate by immunohistochemistry their localization and distribution at this level. A clear
immunopositive reaction was obtained in human lung sections by using either anti-VPAC1 …
potent bronchodilators and secretory agents. By using RT-PCR and immunoblotting
techniques, we have previously shown the expression of common VIP/PACAP (VPAC1 and
VPAC2) and specific PACAP (PAC1) receptors in human lung. Here we extend our aims to
investigate by immunohistochemistry their localization and distribution at this level. A clear
immunopositive reaction was obtained in human lung sections by using either anti-VPAC1 …