Extraction of a highly potent penicillin inactivator from penicillin resistant staphylococci

WMM Kirby - Science, 1944 - science.org
WMM Kirby
Science, 1944science.org
SPECIAL ARTICLES Page 1 VOL. 99, No. 2579 1931 it raged in river valleys northwest of Natal,
but the period between 1932 and 1937 is referred to as the "silent era" because, although' it
was extending its range, the mosquito caused no noticeable increase in malaria. The epidemic
of 1938 in the Jaguaribe valley, in the state of Ceara and along the coast and rivers of the
state of Rio Grande do Norte was catastrophic. It was estimated that in June and July there
were 100,000 cases of malaria with over 14,000 deaths. In 1939 more than 185,000 people …
A highly potent penicillin inactivator has been extracted from 7 strains of Staph. aureus (coagulase positive), all of which were naturally penicillin resistant. No such inhibitor was present in extracts of 7 penicillin sensitive strains of Staph. aureus.
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