[HTML][HTML] Characterization of the human cysteinyl leukotriene 2 receptor
CE Heise, BF O'Dowd, DJ Figueroa, N Sawyer… - Journal of Biological …, 2000 - ASBMB
The contractile and inflammatory actions of the cysteinyl leukotrienes (CysLTs), LTC 4, LTD
4, and LTE 4, are thought to be mediated through at least two distinct but related CysLT G
protein-coupled receptors. The human CysLT 1 receptor has been recently cloned and
characterized. We describe here the cloning and characterization of the second cysteinyl
leukotriene receptor, CysLT 2, a 346-amino acid protein with 38% amino acid identity to the
CysLT 1 receptor. The recombinant human CysLT 2 receptor was expressed in …
4, and LTE 4, are thought to be mediated through at least two distinct but related CysLT G
protein-coupled receptors. The human CysLT 1 receptor has been recently cloned and
characterized. We describe here the cloning and characterization of the second cysteinyl
leukotriene receptor, CysLT 2, a 346-amino acid protein with 38% amino acid identity to the
CysLT 1 receptor. The recombinant human CysLT 2 receptor was expressed in …