Food allergen (peanut)–specific T H2 clones generated from the peripheral blood of a patient with peanut allergy
EC de Jong, S Spanhaak, BPM Martens… - Journal of allergy and …, 1996 - Elsevier
Background: Increasing evidence indicates a prominent role of allergen-specific T H2 cells,
with high IL-4 and IL-5 production and low interferon-γ production, in the regulation of IgE
and eosinophil production in allergic disorders. However, most studies have concentrated
on T cells reactive with inhalation allergens, whereas little is known about the properties of
food allergen–reactive T cells. Objective: In this study we therefore characterized peanut-
specific T cells, cloned from a patient with severe peanut allergy. Methods: Peripheral blood …
with high IL-4 and IL-5 production and low interferon-γ production, in the regulation of IgE
and eosinophil production in allergic disorders. However, most studies have concentrated
on T cells reactive with inhalation allergens, whereas little is known about the properties of
food allergen–reactive T cells. Objective: In this study we therefore characterized peanut-
specific T cells, cloned from a patient with severe peanut allergy. Methods: Peripheral blood …