[HTML][HTML] Transmembrane helix M6 in sarco (endo) plasmic reticulum Ca2+-ATPase forms a functional interaction site with phospholamban: evidence for physical …
M Asahi, Y Kimura, K Kurzydlowski, M Tada… - Journal of Biological …, 1999 - ASBMB
In an earlier study (Kimura, Y., Kurzydlowski, K., Tada, M., and MacLennan, DH (1997) J.
Biol. Chem. 272, 15061–15064), mutation of amino acids on one face of the
phospholamban (PLN) transmembrane helix led to loss of PLN inhibition of sarco (endo)
plasmic reticulum Ca 2+-ATPase (SERCA) molecules. This helical face was proposed to
form a site of PLN interaction with a transmembrane helix in SERCA molecules. To
determine whether predicted transmembrane helices M4, M5, M6, or M8 in SERCA1a …
Biol. Chem. 272, 15061–15064), mutation of amino acids on one face of the
phospholamban (PLN) transmembrane helix led to loss of PLN inhibition of sarco (endo)
plasmic reticulum Ca 2+-ATPase (SERCA) molecules. This helical face was proposed to
form a site of PLN interaction with a transmembrane helix in SERCA molecules. To
determine whether predicted transmembrane helices M4, M5, M6, or M8 in SERCA1a …