FTY720: a novel transplantation drug that modulates lymphocyte traffic rather than activation

V Brinkmann, D Pinschewer, K Chiba, L Feng - Trends in Pharmacological …, 2000 - cell.com
V Brinkmann, D Pinschewer, K Chiba, L Feng
Trends in Pharmacological Sciences, 2000cell.com
7 (6–7) 7 (6–7) 7 (6–7) 0.1 11 (9–12) ND ND 0.3 16 (14–19) ND 7 (7–9) 1 20 (18–21) ND 9
(8–10) 3 23 (20–25) 8 (8–9) 11 (10–12) 10 ND 11 (10–12) 22 (20–23) 30 ND 21 (19–22) ND
aWKAH skin grafted to F344 recipients; drugs were delivered orally, once a day (n 8).
Abbreviations: CsA, cyclosporin A; MST, mean survival time; ND, not determined. WKAH and
F344 are strains of rats.
7 (6–7) 7 (6–7) 7 (6–7) 0.1 11 (9–12) ND ND 0.3 16 (14–19) ND 7 (7–9) 1 20 (18–21) ND 9 (8–10) 3 23 (20–25) 8 (8–9) 11 (10–12) 10 ND 11 (10–12) 22 (20–23) 30 ND 21 (19–22) ND aWKAH skin grafted to F344 recipients; drugs were delivered orally, once a day (n 8). Abbreviations: CsA, cyclosporin A; MST, mean survival time; ND, not determined. WKAH and F344 are strains of rats.
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