Preeclampsia is associated with reduced serum levels of placenta growth factor

DS Torry, HS Wang, TH Wang, MR Caudle… - American journal of …, 1998 - Elsevier
Objectives: Adequate vascular development of the placental bed is essential for normal
pregnancy. We assessed serum levels of placenta growth factor, an angiogenic factor,
throughout normal pregnancy and determined its association with preeclampsia. Study
Design: Serum samples were collected from (1) 308 healthy pregnant women throughout
normal gestation,(2) at delivery from 30 each gestational age–matched patients with normal
pregnancy and preeclampsia, and (3) maternal and cord blood samples from normal …