Compartmentalisation of cAMP and Ca2+ signals
M Zaccolo, P Magalhães, T Pozzan - Current opinion in cell biology, 2002 - Elsevier
M Zaccolo, P Magalhães, T Pozzan
Current opinion in cell biology, 2002•ElsevierThe available knowledge concerning second messengers such as Ca2+ and cAMP has
grown immensely in the past few years. The concept of tight spatial compartmentalisation of
these signals within cells has led to more refined models of intracellular signalling. The
development of recombinant probes based on the green fluorescent protein have allowed
the monitoring of these second messenger levels in single cells, with high spatial and
temporal resolution.
grown immensely in the past few years. The concept of tight spatial compartmentalisation of
these signals within cells has led to more refined models of intracellular signalling. The
development of recombinant probes based on the green fluorescent protein have allowed
the monitoring of these second messenger levels in single cells, with high spatial and
temporal resolution.
The available knowledge concerning second messengers such as Ca2+ and cAMP has grown immensely in the past few years. The concept of tight spatial compartmentalisation of these signals within cells has led to more refined models of intracellular signalling. The development of recombinant probes based on the green fluorescent protein have allowed the monitoring of these second messenger levels in single cells, with high spatial and temporal resolution.
Elsevier