[HTML][HTML] Lipoprotein lipase expression level influences tissue clearance of chylomicron retinyl ester
AM van Bennekum, Y Kako, PH Weinstock… - Journal of lipid …, 1999 - ASBMB
Approximately 25% of postprandial retinoid is cleared from the circulation by extrahepatic
tissues. Little is known about physiologic factors important to this uptake. We hypothesized
that lipoprotein lipase (LpL) contributes to extrahepatic clearance of chylomicron vitamin A.
To investigate this,[3 H] retinyl ester-containing rat mesenteric chylomicrons were injected
intravenously into induced mutant mice and nutritionally manipulated rats. The tissue sites of
uptake of 3 H label by wild type mice and LpL-null mice overexpressing human LpL in …
tissues. Little is known about physiologic factors important to this uptake. We hypothesized
that lipoprotein lipase (LpL) contributes to extrahepatic clearance of chylomicron vitamin A.
To investigate this,[3 H] retinyl ester-containing rat mesenteric chylomicrons were injected
intravenously into induced mutant mice and nutritionally manipulated rats. The tissue sites of
uptake of 3 H label by wild type mice and LpL-null mice overexpressing human LpL in …