Induction of myelin-associated glycoprotein expression through neuron–oligodendrocyte contact
Y Matsuda, H Koito, H Yamamoto - Developmental brain research, 1997 - Elsevier
The role of neurons on expression of myelin-associated glycoprotein (MAG) in
oligodendrocytes and oligodendroglial differentiation was examined. Primary cultures of
oligodendrocytes prepared from neonatal mouse brains were co-cultured with neuronal
cells derived from embryonal carcinoma P19 cells. The levels of MAG mRNAs following this
co-culture were determined by reverse transcription (RT)-PCR. In oligodendrocytes co-
cultured in direct contact with P19-derived neurons, the levels of MAG mRNAs, particularly …
oligodendrocytes and oligodendroglial differentiation was examined. Primary cultures of
oligodendrocytes prepared from neonatal mouse brains were co-cultured with neuronal
cells derived from embryonal carcinoma P19 cells. The levels of MAG mRNAs following this
co-culture were determined by reverse transcription (RT)-PCR. In oligodendrocytes co-
cultured in direct contact with P19-derived neurons, the levels of MAG mRNAs, particularly …