High density lipoprotein as a protective factor against coronary heart disease: the Framingham Study

T Gordon, WP Castelli, MC Hjortland… - The American journal of …, 1977 - Elsevier
Lipid and lipoproiein values, including fasting triglycerides and high density lipoproteins
(HDL), low density llpoproteins (LDL) and total cholesterol levels, were obtained on 2,815
men and women aged 49 to 82 years chiefly between 1969 and 1971 at Framingham. In the
approximately four years following the characterization of lipids, coronary heart disease
developed in 79 of the 1,025 men and 63 of the 1,445 women free of coronary heart
diseases. At these older ages the major potent lipid risk factor was HDL cholesterol, which …