Effects of matrix metalloproteinase inhibitor BB-94 on liver cancer growth and metastasis in a patient-like orthotopic model LCI-D20.
W Bu, ZY Tang, FX Sun, SL Ye, KD Liu… - Hepato …, 1998 - europepmc.org
W Bu, ZY Tang, FX Sun, SL Ye, KD Liu, Q Xue, J Chen, DM Gao
Hepato-gastroenterology, 1998•europepmc.orgEffects of matrix metalloproteinase inhibitor BB-94 on liver cancer growth and metastasis in a
patient-like orthotopic model LCI-D20. - Abstract - Europe PMC Sign in | Create an account
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Results
BB-94 can inhibit primary tumor growth, local invasion, intrahepatic and lung metastasis, as well as prolong survival. BB-94 did not affect the proliferation of HCC cells in vitro. LCI-D20 tumor tissue expresses MMP-2 and MMP-9.
Conclusions
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