Mitochondrial control of cell death

G Kroemer, JC Reed - Nature medicine, 2000 - nature.com
G Kroemer, JC Reed
Nature medicine, 2000nature.com
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Abstract
In many instances, permeabilization of mitochondrial membranes is a rate-limiting step of apoptotic or necrotic cell demise. This has important consequences for the pathophysiology of cell death, as well as for its pharmacological control.
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