Publisher Summary Animal models, including guinea pigs, monkeys, rats, and mice are
used to study the pathogenesis of asthma. Mouse models of allergic lung disease are
utilized to dissect the complex pathophysiological mechanisms underlying the asthma
phenotype. The airways of patients with even mild asthma are inflamed, and some data
suggest that the severity of asthma parallels the degree of this inflammation. The animal
models are enabling to highlight specific pathways and to give the opportunity to study the …