Calcitonin for prevention and treatment of osteoporosis

JY Reginster - The American journal of medicine, 1993 - Elsevier
There appears to be a consensus that 100 IU/day of nasally administered salmon calcitonin
may prevent trabecular bone loss during the first years of the menopause. Strong evidence
exists that half that dose may also be sufficient to prevent trabecular bone loss and that
higher doses (≥ 200 IU/day) induce a significant increase in spinal bone mineral content.
Calcium supplements should be systemically administered when calcitonin is given,
particularly at high doses. Rectal calcitonin seems also to be an efficient alternative in …