Long-term renoprotective effect of angiotensin-converting enzyme inhibition in non—insulin-dependent diabetes mellitus: a 7-year follow-up study
M Ravid, R Lang, R Rachmani… - Archives of internal …, 1996 - jamanetwork.com
Background: Diabetic nephropathy is the leading cause of end-stage renal disease in
developed countries. Duration of diabetes, blood pressure values, and metabolic status are
the major determinants of the course of nephropathy, and microalbuminuria is the hallmark
of its onset. Angiotensin-converting enzyme inhibitors offer important renoprotection to
hypertensive and normotensive patients with insulin-dependent diabetes mellitus and non—
insulin-dependent diabetes mellitus. Our study extends previous observations for duration …
developed countries. Duration of diabetes, blood pressure values, and metabolic status are
the major determinants of the course of nephropathy, and microalbuminuria is the hallmark
of its onset. Angiotensin-converting enzyme inhibitors offer important renoprotection to
hypertensive and normotensive patients with insulin-dependent diabetes mellitus and non—
insulin-dependent diabetes mellitus. Our study extends previous observations for duration …