Steroid therapy in acute cerebral infarction
JW Norris - Archives of Neurology, 1976 - jamanetwork.com
• Fifty-three patients with acute cerebral infarction were treated in a doubleblind study with
either dexamethasone or placebo within 24 hours of the onset of stroke. Forty-one of these
survived for longer than 28 days, and the patients treated with the steroid fared slightly
worse than those treated with placebo at the end of this time. Two of the five patients who
died in the placebo group died of cerebral edema, compared with three out of seven patients
who died in the steroid group. Infectious complications, gastrointestinal hemorrhage, and …
either dexamethasone or placebo within 24 hours of the onset of stroke. Forty-one of these
survived for longer than 28 days, and the patients treated with the steroid fared slightly
worse than those treated with placebo at the end of this time. Two of the five patients who
died in the placebo group died of cerebral edema, compared with three out of seven patients
who died in the steroid group. Infectious complications, gastrointestinal hemorrhage, and …