Multicentre study on intensified remission induction therapy for acute myeloid leukemia

T Büchner, D Urbanitz, B Emmerich, JT Fischer… - Leukemia Research, 1982 - Elsevier
In a cooperative study at 13 centres in the Federal Republic of Germany, 213 adult patients
with AML were treated for remission induction by a 9-day regimen consisting of cytosine
arabinoside, daunorubicin and thioguanine (TAD) according to previously described
sequencing. Complete remission was achieved in 70% of all patients. Complete remission
rate was 57% in the 49 patients 60 years of age and older and 74% in the 164 patients
under 60 years. Sixty-eight per cent of all complete remissions and 75% of those in the …