Corticosteroids alone or in conjunction with azathioprine is the treatment of choice in
patients with autoimmune hepatitis (AIH) and results in remission induction in over 80% of
patients. Sustained response to therapy may result in substantial regression of fibrosis even
in advanced cases. The outcome of rapid withdrawal of immunosuppression is disease
relapse in many patients. Consequently, the use of 2 mg/kg/d of azathioprine as a sole agent
to maintain remission has been widely accepted in clinical practice. Persistent severe …