The role of the map protein in Staphylococcus aureus matrix protein and eukaryotic cell adherence
B Kreikemeyer, D McDevitt, A Podbielski - International journal of medical …, 2002 - Elsevier
The Staphylococcus aureus Map protein was proposed to act as a multifunctional adhesin.
Using a map− mutant, a complemented strain and recombinant Map, we demonstrated that
Map was not a conventional adhesin and was not involved in binding soluble extracellular
matrix (ECM) proteins and in staphylococcal adherence to immobilized ECM proteins.
However, Map provided a substrate for efficient and species-specific adherence of
staphylococcal cells. This interaction was dose-dependent and was inhibited by specific anti …
Using a map− mutant, a complemented strain and recombinant Map, we demonstrated that
Map was not a conventional adhesin and was not involved in binding soluble extracellular
matrix (ECM) proteins and in staphylococcal adherence to immobilized ECM proteins.
However, Map provided a substrate for efficient and species-specific adherence of
staphylococcal cells. This interaction was dose-dependent and was inhibited by specific anti …