Staphylococcus aureus is an important pathogen capable of causing a wide spectrum of
diseases in humans and animals. This bacterium expresses a variety of virulence factors
that participate in the process of infection. These include MSCRAMMs (microbial surface
componentsrecognizing adhesive matrixmolecules) that mediate the adherence of the
bacteria to host extracellular matrix components, such as collagen, fibronectin (Fn), and
fibrinogen (Fg). Two Fn-binding MSCRAMMs, FnbpA and FnbpB, have been previously …