Staphylococcus aureus adhesion to bone matrix and bone-associated biomaterials

MC Hudson, WK Ramp… - FEMS microbiology …, 1999 - academic.oup.com
MC Hudson, WK Ramp, KP Frankenburg
FEMS microbiology letters, 1999academic.oup.com
Staphylococcus aureus is a frequent cause of orthopedic infections in humans. The
bacterium expresses several adhesins that facilitate bacterial binding to the bone matrix and
to bone implant biomaterials coated with host plasma constituents. The relevant S. aureus
adhesins are termed microbial surface components recognizing adhesive matrix molecules
(MSCRAMMs) and specific MSCRAMMs are involved in bone and joint infections.
Abstract
Staphylococcus aureus is a frequent cause of orthopedic infections in humans. The bacterium expresses several adhesins that facilitate bacterial binding to the bone matrix and to bone implant biomaterials coated with host plasma constituents. The relevant S. aureus adhesins are termed microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) and specific MSCRAMMs are involved in bone and joint infections.
Oxford University Press