Follicular dendritic cells initiate and maintain infection of the germinal centers by human immunodeficiency virus
K Tenner-Racz, P Racz - An Antigen Depository of the Immune System …, 1995 - Springer
K Tenner-Racz, P Racz
An Antigen Depository of the Immune System: Follicular Dendritic Cells, 1995•SpringerSince the discovery of the human immunodeficiency virus type 1 (HIV-1) as the cause of the
acquired immunodeficiency syndrome (AIDS), careful attention has been paid to the
preference of the virus for specific cells. However, the preference of HIV-1 for specific host
tissues or tissue compartments such as germinal centers (GC) of the lymphoid tissue was
often overlooked. Application of electronmicroscopic, immunohistochemical, and nucleic
acid hybridization techniques to the study of lymphoid tissues led to the demonstration that …
acquired immunodeficiency syndrome (AIDS), careful attention has been paid to the
preference of the virus for specific cells. However, the preference of HIV-1 for specific host
tissues or tissue compartments such as germinal centers (GC) of the lymphoid tissue was
often overlooked. Application of electronmicroscopic, immunohistochemical, and nucleic
acid hybridization techniques to the study of lymphoid tissues led to the demonstration that …
Abstract
Since the discovery of the human immunodeficiency virus type 1 (HIV-1) as the cause of the acquired immunodeficiency syndrome (AIDS), careful attention has been paid to the preference of the virus for specific cells. However, the preference of HIV-1 for specific host tissues or tissue compartments such as germinal centers (GC) of the lymphoid tissue was often overlooked. Application of electronmicroscopic, immunohistochemical, and nucleic acid hybridization techniques to the study of lymphoid tissues led to the demonstration that GC are infected by HIV-1 and improved our understanding of the pathogenesis of AIDS.
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