Hereditary sensory neuropathy: association with increased synthesis of immunoglobulin A
JN Whitaker, ZM Falchuck, WK Engel… - Archives of …, 1974 - jamanetwork.com
Increased immunoglobulin A (IgA) levels were detected in nine individuals, from three
unrelated families, who had hereditary sensory neuropathy. Other immunoglobulin levels
were generally normal, and serum IgA was not elevated in unaffected family members. No
accompanying disorder was detected that could have accounted for the
dysgammaglobulinemia. No noteworthy immunologic abnormality besides that of IgA was
present. In a series of metabolic and immunologic studies, it was shown that the increased …
unrelated families, who had hereditary sensory neuropathy. Other immunoglobulin levels
were generally normal, and serum IgA was not elevated in unaffected family members. No
accompanying disorder was detected that could have accounted for the
dysgammaglobulinemia. No noteworthy immunologic abnormality besides that of IgA was
present. In a series of metabolic and immunologic studies, it was shown that the increased …