Distribution and cytokine production of CD4 and CD8 T-lymphocyte subsets in patients with acute asthma attacks
SY Lee, SJ Kim, SS Kwon, YK Kim, KH Kim… - Annals of Allergy …, 2001 - Elsevier
BACKGROUND: The activation of T cells and the elevation of Th2-type cytokines have been
observed in asthmatic patients, but the relative role of CD4 and CD8 T cell is still unclear.
OBJECTIVE: To investigate the role of T cell subset in patients with acute asthma attacks, we
analyzed the distribution, activation status, and cytokine production of CD4 and CD8 cells.
METHODS: The percentages of the CD4 and CD8 cell in peripheral blood (PB) and
bronchoalveolar lavage (BAL) fluid were analyzed by flow cytometry. The cytokines (IL-4, IL …
observed in asthmatic patients, but the relative role of CD4 and CD8 T cell is still unclear.
OBJECTIVE: To investigate the role of T cell subset in patients with acute asthma attacks, we
analyzed the distribution, activation status, and cytokine production of CD4 and CD8 cells.
METHODS: The percentages of the CD4 and CD8 cell in peripheral blood (PB) and
bronchoalveolar lavage (BAL) fluid were analyzed by flow cytometry. The cytokines (IL-4, IL …