[HTML][HTML] Genetic analysis of intestinal cholesterol absorption in inbred mice
M Schwarz, DL Davis, BR Vick, DW Russell - Journal of lipid research, 2001 - ASBMB
A genetic mapping strategy was employed to identify chromosomal regions harboring genes
that influence the absorption of intestinal cholesterol in the mouse. Analysis of seven inbred
strains of male mice (129P3, AKR, BALB/c, C3H/He, C57BL/6, DBA/2, and SJL, all from
Jackson Laboratories) revealed substantial differences in their abilities to absorb a bolus of
cholesterol delivered by gavage. Crosses between high (AKR, 129) and low (DBA/2, SJL)
absorbing strains revealed evidence for the presence of dominant genes that increase and …
that influence the absorption of intestinal cholesterol in the mouse. Analysis of seven inbred
strains of male mice (129P3, AKR, BALB/c, C3H/He, C57BL/6, DBA/2, and SJL, all from
Jackson Laboratories) revealed substantial differences in their abilities to absorb a bolus of
cholesterol delivered by gavage. Crosses between high (AKR, 129) and low (DBA/2, SJL)
absorbing strains revealed evidence for the presence of dominant genes that increase and …