AT cell epitope for experimental allergic neuritis
T Olee, JM Powers, SW Brostoff - Journal of neuroimmunology, 1988 - Elsevier
A synthetic peptide representing residues 57–81 of the bovine P 2 protein produced severe
paralytic experimental allergic neuritis (EAN) in Lewis rats. Peptide 57–81 could also be
used to stimulate a P 2 protein-specific T cell line to transfer paralytic EAN to naive recipient
rats. A smaller peptide representing residues 60–81 produced a milder form of clinical
disease. Residues 60–81 are the shortest peptide sequence thus far described which can
produce clinical EAN. The structural predictions for the sequence represented by these …
paralytic experimental allergic neuritis (EAN) in Lewis rats. Peptide 57–81 could also be
used to stimulate a P 2 protein-specific T cell line to transfer paralytic EAN to naive recipient
rats. A smaller peptide representing residues 60–81 produced a milder form of clinical
disease. Residues 60–81 are the shortest peptide sequence thus far described which can
produce clinical EAN. The structural predictions for the sequence represented by these …