Intestinal cholesterol absorption
PA Dawson, LL Rudel - Current opinion in lipidology, 1999 - journals.lww.com
PA Dawson, LL Rudel
Current opinion in lipidology, 1999•journals.lww.comThe strong association between intestinal cholesterol absorption and total plasma
cholesterol level has renewed interest in the absorptive process and stimulated the
generation of new animal models. Increasingly, new studies suggest that cholesterol
absorption is genetically controlled and supports a protein-mediated mechanism for
cholesterol uptake into the intestinal mucosal cell. Insights into potential mechanisms are
predicted to lead to novel pharmacological approaches to inhibit cholesterol absorption.
cholesterol level has renewed interest in the absorptive process and stimulated the
generation of new animal models. Increasingly, new studies suggest that cholesterol
absorption is genetically controlled and supports a protein-mediated mechanism for
cholesterol uptake into the intestinal mucosal cell. Insights into potential mechanisms are
predicted to lead to novel pharmacological approaches to inhibit cholesterol absorption.
Abstract
The strong association between intestinal cholesterol absorption and total plasma cholesterol level has renewed interest in the absorptive process and stimulated the generation of new animal models. Increasingly, new studies suggest that cholesterol absorption is genetically controlled and supports a protein-mediated mechanism for cholesterol uptake into the intestinal mucosal cell. Insights into potential mechanisms are predicted to lead to novel pharmacological approaches to inhibit cholesterol absorption.
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