Differential expression of prostanoid receptors in hepatocytes, Kupffer cells, sinusoidal endothelial cells and stellate cells of rat liver
A Fennekohl, HL Schieferdecker, K Jungermann… - Journal of …, 1999 - Elsevier
Background/Aims: Prostanoids produced by nonparenchymal cells modulate the function of
parenchymal and nonparenchymal liver cells during homeostasis and inflammation via eight
classes of prostanoid receptors coupled to different G-proteins. Prostanoid receptor
expression in parenchymal and nonparenchymal cells was studied in order to get a better
insight into the complex prostanoid-mediated intrahepatic signaling network. Methods: RNA
was isolated from freshly purified parenchymal and nonparenchymal rat liver cells and the …
parenchymal and nonparenchymal liver cells during homeostasis and inflammation via eight
classes of prostanoid receptors coupled to different G-proteins. Prostanoid receptor
expression in parenchymal and nonparenchymal cells was studied in order to get a better
insight into the complex prostanoid-mediated intrahepatic signaling network. Methods: RNA
was isolated from freshly purified parenchymal and nonparenchymal rat liver cells and the …