Reduction of interstitial fluid pressure after TNF-alpha treatment of three human melanoma xenografts

CA Kristensen, M Nozue, Y Boucher, RK Jain - British journal of cancer, 1996 - nature.com
CA Kristensen, M Nozue, Y Boucher, RK Jain
British journal of cancer, 1996nature.com
Reduction of interstitial fluid pressure after TNF-oa treatment of three human melanoma
xenografts Page 1 British Jounal of Cancer (1996) 74, 533-536 © 1996 Stockton Press AJI
rights reserved 0007-0920/96 $12.00 * SHORT COMMUNICATION Reduction of interstitial fluid
pressure after TNF-oa treatment of three human melanoma xenografts CA Kristensen, M Nozue,
Y Boucher and RK Jain Edwin L Steele Laboratory, Harvard Medical School, Massachusetts
General Hospital, 100 Blossom Street, Boston, MA 02114, USA. Summary Tumour necrosis …
Abstract
Tumour necrosis factor-alpha (TNF-alpha) reduced the interstitial fluid pressure (IFP) to 54-64%(P< 0.05) and the mean arterial blood pressure (MABP) to 70%(P< 0.01) of control values after 5 h in three human melanoma tumour lines transplanted to nude mice.
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