Elevated second-trimester amniotic fluid concentration of insulin-like growth factor binding protein-1 in fetal growth retardation
TH Hakala-Ala-Pietilä, RA Koistinen… - American journal of …, 1993 - Elsevier
Objective: The aim was to study the levels of amniotic fluid and maternal serum insulin-like
growth factor binding protein-1 levels at 15 to 16 weeks' gestation with regard to fetal growth
in the third trimester. Study Design: Amniotic fluid (n= 148) and maternal serum (n= 129)
levels of insulin-like growth factor binding protein-1 were prospectively measured. Results:
Elevated amniotic fluid insulin-like growth factor binding protein-1 levels were related to fetal
growth retardation. At a cutoff value of 3 multiples of the median a high-risk group …
growth factor binding protein-1 levels at 15 to 16 weeks' gestation with regard to fetal growth
in the third trimester. Study Design: Amniotic fluid (n= 148) and maternal serum (n= 129)
levels of insulin-like growth factor binding protein-1 were prospectively measured. Results:
Elevated amniotic fluid insulin-like growth factor binding protein-1 levels were related to fetal
growth retardation. At a cutoff value of 3 multiples of the median a high-risk group …