Stereological evaluation of vascular adaptations in human placental villi to differing forms of hypoxic stress
GJ Burton, OS Reshetnikova, AP Milovanov… - Placenta, 1996 - Elsevier
The aim was to determine whether the fetal vasculature of the human placenta adapts in a
uniform manner to different forms of hypoxic stress. Stereological analyses were performed
on the intermediate and terminal villi of placentae obtained from each of the following
conditions; high altitude (up to 2800 m), maternal iron-deficiency anaemia and pre-
eclampsia. These conditions were taken to represent hypoxic, anaemic and ischaemic
hypoxia, respectively. In each situation, there was a trend for the volume fraction of the fetal …
uniform manner to different forms of hypoxic stress. Stereological analyses were performed
on the intermediate and terminal villi of placentae obtained from each of the following
conditions; high altitude (up to 2800 m), maternal iron-deficiency anaemia and pre-
eclampsia. These conditions were taken to represent hypoxic, anaemic and ischaemic
hypoxia, respectively. In each situation, there was a trend for the volume fraction of the fetal …