C-kit ligand (Stem Cell Factor) affects neuronal activity, stimulates pituitary-adrenal axis and prolactin secretion in rats

KJ Kovács, A Földes, ES Vizi - Journal of neuroimmunology, 1996 - Elsevier
Stem Cell Factor (SCF) is a potent growth factor affecting proliferation, differentiation and
migration as well as secretory functions of various cells of different origin and function. The
effect of SCF on neuronal activity and on neuroendocrine regulation has been studied by
injecting SCF iV into conscious male rats. Administration of SCF elevated
adrenocorticotropin (ACTH), corticosterone and prolactin (PRL) plasma levels in a dose-
dependent manner. Adrenocorticotropin and corticosterone secretions were maximal after …