Effectiveness of 1, 25-dihydroxyvitamin D supplementation on blood pressure reduction in a pseudohypoparathyroidism patient with high renin activity
Y Kimura, M Kawamura, M Owada, T Oshima… - Internal …, 1999 - jstage.jst.go.jp
Y Kimura, M Kawamura, M Owada, T Oshima, M MUROOKA, T FUJIWARA, K HIRAMORI
Internal medicine, 1999•jstage.jst.go.jpA42-year-old manhad biochemical andsomatic abnormalities compatible with
pseudohypoparathyroidism type I (PsHP) and also had high plasma renin activity (PRA).
After 1, 25-dihydroxyvitamin D (calcitriol) supplementation the systolic/diastolic blood
pressure, assessed by 24-hour non-invasive ambulatory blood pressure monitoring,
wasreduced from 145/96 mmHgto 128/85 mmHgwith normalization of the serum calcium
level and its related hormones, as well as decreased PRA. Calcitriol supplementation …
pseudohypoparathyroidism type I (PsHP) and also had high plasma renin activity (PRA).
After 1, 25-dihydroxyvitamin D (calcitriol) supplementation the systolic/diastolic blood
pressure, assessed by 24-hour non-invasive ambulatory blood pressure monitoring,
wasreduced from 145/96 mmHgto 128/85 mmHgwith normalization of the serum calcium
level and its related hormones, as well as decreased PRA. Calcitriol supplementation …
A42-year-old manhad biochemical andsomatic abnormalities compatible with pseudohypoparathyroidism type I (PsHP) and also had high plasma renin activity (PRA). After 1, 25-dihydroxyvitamin D (calcitriol) supplementation the systolic/diastolic blood pressure, assessed by 24-hour non-invasive ambulatory blood pressure monitoring, wasreduced from 145/96 mmHgto 128/85 mmHgwith normalization of the serum calcium level and its related hormones, as well as decreased PRA. Calcitriol supplementation successfully reduced the blood pressure in this patient with PsHPand a high PRA, suggesting that calcium-related hormones and/or the renin-angiotensin system were involved in lowering the blood pressure.(Internal Medicine 38: 31-35, 1999)
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