Consumption of NSAIDs and the development of congestive heart failure in elderly patients: an underrecognized public health problem
J Page, D Henry - Archives of internal medicine, 2000 - jamanetwork.com
Background Experimental studies have shown that administration of nonsteroidal anti-
inflammatory drugs (NSAIDs) to susceptible individuals can lead to the development of
congestive heart failure (CHF). There have been few epidemiological investigations of the
importance of this adverse effect. Objective To estimate the relative risk of first admission to a
hospital with CHF in recent users of NSAIDs, compared with nonusers, and to determine
whether the estimated relative risk was increased in those with a history of heart disease …
inflammatory drugs (NSAIDs) to susceptible individuals can lead to the development of
congestive heart failure (CHF). There have been few epidemiological investigations of the
importance of this adverse effect. Objective To estimate the relative risk of first admission to a
hospital with CHF in recent users of NSAIDs, compared with nonusers, and to determine
whether the estimated relative risk was increased in those with a history of heart disease …