[HTML][HTML] Changes in the lipid turnover, composition, and organization, as sphingolipid-enriched membrane domains, in rat cerebellar granule cells developing in vitro

A Prinetti, V Chigorno, S Prioni, N Loberto… - Journal of Biological …, 2001 - ASBMB
In the present paper, we report on the properties of sphingolipid-enriched domains of rat
cerebellar granule cells in culture at different stages of neuronal development. The major
lipid components of these domains were glycerophospholipids and cholesterol.
Glycerophospholipids were 45–75‥ and cholesterol 15–45‥ of total lipids of the domains.
This corresponded to 5–17‥ of total cell glycerophospholipids and 15–45‥ of total cell
cholesterol. Phosphatidylcholine, mainly dipalmitoylphosphatidylcholine, was 66–85‥ of all …