The control of immune responses by sex hormones is well documented but the effect of sex
hormones on lymphoid cell subsets is poorly understood. We have investigated the
expression of receptors for androgens (AR), estradiol (ER) and progesterone (PR) by human
cell lines of the B lymphocyte lineage and by murine myeloma or hybridomas. AR, ER and
PR were determined by cytosol and nuclear binding assays. Eleven human lymphoblastoid
cell lines obtained by in virto infection of blood or tonsil B cells with Epstein-Barr Virus (EBV) …