To date a multitude of studies into the morphology and neurochemistry of human epilepsy
have been undertaken with variable, and often inconsistent, results. This review summarises
these studies on a range of neurotransmitters, neuromodulators, neuropeptides and their
receptors. In addition to this, novel changes in cell viability and sprouting have been
identified and are discussed. Whether the alterations observed are a result of the seizures or
are a contributory factor is unclear. However, it may be that following an initial insult (such as …