[HTML][HTML] Exploiting dendritic cells to improve vaccine efficacy
RM Steinman, M Pope - The Journal of clinical investigation, 2002 - Am Soc Clin Investig
RM Steinman, M Pope
The Journal of clinical investigation, 2002•Am Soc Clin InvestigCD8+ T cells even when delivered to the DCs in poorly replicating vectors and as ultraviolet
light and chemically inactivated virions. The potency of DCs in stimulating T cells in vitro
reflects both their specialized ability to capture and present antigens and the effects of other
molecules, not present in MHC complexes, that enhance T cell binding and stimulation.
light and chemically inactivated virions. The potency of DCs in stimulating T cells in vitro
reflects both their specialized ability to capture and present antigens and the effects of other
molecules, not present in MHC complexes, that enhance T cell binding and stimulation.
CD8+ T cells even when delivered to the DCs in poorly replicating vectors and as ultraviolet light and chemically inactivated virions. The potency of DCs in stimulating T cells in vitro reflects both their specialized ability to capture and present antigens and the effects of other molecules, not present in MHC complexes, that enhance T cell binding and stimulation.
The Journal of Clinical Investigation