[HTML][HTML] Ca2+/calmodulin-dependent protein kinase IV is expressed in spermatids and targeted to chromatin and the nuclear matrix
JY Wu, AR Means - Journal of Biological Chemistry, 2000 - ASBMB
Ca 2+/calmodulin-dependent protein kinase IV and calspermin are two proteins encoded by
theCamk4 gene. Both are highly expressed in the testis, wherein situ hybridization studies in
rat testes have demonstrated that CaMKIV mRNA is localized to pachytene spermatocytes,
while calspermin mRNA is restricted to spermatids. We have examined the expression
patterns of both CaMKIV and calspermin in mouse testis and unexpectedly find that CaMKIV
is expressed in spermatogonia and spermatids but excluded from spermatocytes, while …
theCamk4 gene. Both are highly expressed in the testis, wherein situ hybridization studies in
rat testes have demonstrated that CaMKIV mRNA is localized to pachytene spermatocytes,
while calspermin mRNA is restricted to spermatids. We have examined the expression
patterns of both CaMKIV and calspermin in mouse testis and unexpectedly find that CaMKIV
is expressed in spermatogonia and spermatids but excluded from spermatocytes, while …