[CITATION][C] [21] Analysis of signal transduction following lymphocyte activation by chemokines
KB Bacon - Methods in enzymology, 1997 - Elsevier
The chemokines are a superfamily of small molecular mass proteins related in primary
structure by the conservation of a four-cysteine motif. 1'2 Presently, the superfamily is
subdivided into three subgroups: the CXC family, typified by members such as interleukin-8
(IL-8), growth-related oncogene (GRO-a), and neutrophil-activating peptide-2 (NAP-2),
retains all four N-terminal cysteines with the first two being separated by a single intervening
amino acid. The CC family, typified by members such as RANTES, macrophage …
structure by the conservation of a four-cysteine motif. 1'2 Presently, the superfamily is
subdivided into three subgroups: the CXC family, typified by members such as interleukin-8
(IL-8), growth-related oncogene (GRO-a), and neutrophil-activating peptide-2 (NAP-2),
retains all four N-terminal cysteines with the first two being separated by a single intervening
amino acid. The CC family, typified by members such as RANTES, macrophage …