The inhibition of plasmin, plasma kallikrein, plasma permeability factor, and the C'1r subcomponent of the first component of complement by serum C'1 esterase …
OD Ratnoff, J Pensky, D Ogston, GB Naff - The Journal of Experimental …, 1969 - rupress.org
OD Ratnoff, J Pensky, D Ogston, GB Naff
The Journal of Experimental Medicine, 1969•rupress.orgThe fraction of human serum designated as C'1 esterase inhibitor is known to inhibit the
action of C'1 esterase, a plasma kallikrein, and PF/Dil, an enzyme in plasma enhancing
cutaneous vascular permeability. In the present study, C'1 esterase inhibitor has been found
to block the actions of plasmin and the C'1r subcomponent of the first component of
complement, and to retard the generation of PF/Dil. No inhibition of blood clotting or of the
generation of plasmin was demonstrable.
action of C'1 esterase, a plasma kallikrein, and PF/Dil, an enzyme in plasma enhancing
cutaneous vascular permeability. In the present study, C'1 esterase inhibitor has been found
to block the actions of plasmin and the C'1r subcomponent of the first component of
complement, and to retard the generation of PF/Dil. No inhibition of blood clotting or of the
generation of plasmin was demonstrable.
The fraction of human serum designated as C'1 esterase inhibitor is known to inhibit the action of C'1 esterase, a plasma kallikrein, and PF/Dil, an enzyme in plasma enhancing cutaneous vascular permeability. In the present study, C'1 esterase inhibitor has been found to block the actions of plasmin and the C'1r subcomponent of the first component of complement, and to retard the generation of PF/Dil. No inhibition of blood clotting or of the generation of plasmin was demonstrable.
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