[HTML][HTML] Identification of novel Pax-2 binding sites by chromatin precipitation
DE Phelps, GR Dressler - Journal of Biological Chemistry, 1996 - ASBMB
The Pax genes encode a family of developmental transcription factors that bind to specific
DNA sequences via the paired domain and are necessary for the morphogenesis of a
variety of tissues. The murine Pax-2 gene, through alternative splicing, encodes two nuclear
proteins, Pax-2A and Pax-2B, which are transiently expressed during the differentiation of
specific neural cell types and early kidney formation. In order to identify potential in vivo Pax-
2 target sequences, chromatin from embryonic neural tube was immunoprecipitated with …
DNA sequences via the paired domain and are necessary for the morphogenesis of a
variety of tissues. The murine Pax-2 gene, through alternative splicing, encodes two nuclear
proteins, Pax-2A and Pax-2B, which are transiently expressed during the differentiation of
specific neural cell types and early kidney formation. In order to identify potential in vivo Pax-
2 target sequences, chromatin from embryonic neural tube was immunoprecipitated with …