Hormonal influences on the secretion of steroid-binding proteins by a human hepatoma-derived cell line
W ROSNER, DP ADEN, MS KHAN - The Journal of Clinical …, 1984 - academic.oup.com
W ROSNER, DP ADEN, MS KHAN
The Journal of Clinical Endocrinology & Metabolism, 1984•academic.oup.comWe examined the influence of numerous substances on the secretion of corticosteroid-
binding globulin (CBG) and testosterone-estradiol binding globulin (TeBG) by a human
hepatoma-derived cell line. Thyroxine, at physiologic concentrations, resulted in an
increased secretion of TeBG but not CBG. Estrogens, antiestrogens, and androgens were
without effect on either of these binding proteins.
binding globulin (CBG) and testosterone-estradiol binding globulin (TeBG) by a human
hepatoma-derived cell line. Thyroxine, at physiologic concentrations, resulted in an
increased secretion of TeBG but not CBG. Estrogens, antiestrogens, and androgens were
without effect on either of these binding proteins.
Abstract
We examined the influence of numerous substances on the secretion of corticosteroid-binding globulin (CBG) and testosterone-estradiol binding globulin (TeBG) by a human hepatoma-derived cell line. Thyroxine, at physiologic concentrations, resulted in an increased secretion of TeBG but not CBG. Estrogens, antiestrogens, and androgens were without effect on either of these binding proteins.
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