Inhibition of vagal vasodilatation by a selective neuropeptide Y Y2 receptor agonist in the bronchial circulation of anaesthetised dogs
DA Mahns, JS Lacroix, EK Potter - Journal of the autonomic nervous …, 1998 - Elsevier
Neuropeptide Y (NPY) is both co-stored and co-released with noradrenaline from
sympathetic nerve terminals. In the cardiovascular system, NPY acts on two main receptor
subtypes. At postjunctional, or Y1 receptors, NPY can cause both direct vasoconstriction and
the potentiation of various constrictor agents. NPY acting at the presynaptic, or Y2 receptor,
inhibits the release of neurotransmitter from autonomic nerves. In the present paper, we
have used both sympathetic stimulation and the selective NPY Y2 receptor agonist, N-acetyl …
sympathetic nerve terminals. In the cardiovascular system, NPY acts on two main receptor
subtypes. At postjunctional, or Y1 receptors, NPY can cause both direct vasoconstriction and
the potentiation of various constrictor agents. NPY acting at the presynaptic, or Y2 receptor,
inhibits the release of neurotransmitter from autonomic nerves. In the present paper, we
have used both sympathetic stimulation and the selective NPY Y2 receptor agonist, N-acetyl …