Nutrient gene regulation is an important adaptation allowing survival on intermittent food
supplies. This adaptative process exists in all species from yeast to mammals. Glucose, the
most abundant monosaccharide in nature, provides a very good example of how organisms
have developed regulatory mechanisms to cope with a fluctuating level of nutrient supply. In
yeast, glucose facilitates its own use by inducing expression of genes involved in its
metabolism while repressing that of those involved in the utilization of alternative carbon …