[HTML][HTML] Macrophage-derived chemokine induces human eosinophil chemotaxis in a CC chemokine receptor 3–and CC chemokine receptor 4–independent manner
BS Bochner, CA Bickel, ML Taylor… - Journal of allergy and …, 1999 - Elsevier
Background: Chemokines are believed to contribute to selective cell recruitment.
Macrophage-derived chemokine (MDC) is a CC chemokine that causes chemotaxis of
dendritic cells, monocytes, and activated natural killer cells. MDC binds to CC chemokine
receptor 4 (CCR4) but not to CCR1, CCR2, CCR3, CCR5, CCR6, or CCR7. Objective: Our
aim was to determine the in vitro activity of MDC on human eosinophils by using chemotaxis
and calcium flux assays. Methods: Eosinophils were purified from peripheral blood of …
Macrophage-derived chemokine (MDC) is a CC chemokine that causes chemotaxis of
dendritic cells, monocytes, and activated natural killer cells. MDC binds to CC chemokine
receptor 4 (CCR4) but not to CCR1, CCR2, CCR3, CCR5, CCR6, or CCR7. Objective: Our
aim was to determine the in vitro activity of MDC on human eosinophils by using chemotaxis
and calcium flux assays. Methods: Eosinophils were purified from peripheral blood of …