[HTML][HTML] Transglutaminase type 1 and its cross-linking activity are concentrated at adherens junctions in simple epithelial cells
T Hiiragi, H Sasaki, A Nagafuchi, H Sabe… - Journal of Biological …, 1999 - ASBMB
Transglutaminase type 1 was identified as a tyrosine-phosphorylated protein from the
isolated junctional fraction of the mouse liver. This enzyme was reported to be involved in
the covalent cross-linking of proteins in keratinocytes, but its expression and activity in other
cell types have not been examined. Northern blotting revealed that transglutaminase type 1
was expressed in large amounts in epithelial tissues (lung, liver, and kidney), which was
also confirmed by immunoblotting with antibodies raised against mouse recombinant …
isolated junctional fraction of the mouse liver. This enzyme was reported to be involved in
the covalent cross-linking of proteins in keratinocytes, but its expression and activity in other
cell types have not been examined. Northern blotting revealed that transglutaminase type 1
was expressed in large amounts in epithelial tissues (lung, liver, and kidney), which was
also confirmed by immunoblotting with antibodies raised against mouse recombinant …